Indian Journal of Dermatology
  Publication of IADVL, WB
  Official organ of AADV
Indexed with Science Citation Index (E) , Web of Science and PubMed
 
Users online: 1109  
Home About  Editorial Board  Current Issue Archives Online Early Coming Soon Guidelines Subscriptions  e-Alerts    Login  
    Small font sizeDefault font sizeIncrease font size Print this page Email this page


 
Table of Contents 
CORRESPONDENCE
Year : 2015  |  Volume : 60  |  Issue : 2  |  Page : 199
Benign lymphangiomatous papules or plaques after radiotherapy is the correct terminology


Department of Dermatology, Venereology and Leprosy, Mahatma Gandhi Institute of Medical Sciences and Kasturba Hospital, Sewagram, Wardha, India

Date of Web Publication3-Mar-2015

Correspondence Address:
Bhushan Madke
Department of Dermatology, Venereology and Leprosy, Mahatma Gandhi Institute of Medical Sciences and Kasturba Hospital, Sewagram, Wardha
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.152533

Rights and Permissions



How to cite this article:
Madke B. Benign lymphangiomatous papules or plaques after radiotherapy is the correct terminology. Indian J Dermatol 2015;60:199

How to cite this URL:
Madke B. Benign lymphangiomatous papules or plaques after radiotherapy is the correct terminology. Indian J Dermatol [serial online] 2015 [cited 2020 Mar 30];60:199. Available from: http://www.e-ijd.org/text.asp?2015/60/2/199/152533


Sir,

I read with interest the paper by Rao in your esteemed journal describing the development of acquired lymphangiectasias in an operated case of breast carcinoma who had received radiotherapy. [1] The author had diagnosed the case as acquired lymphangiectasia following surgery and radiotherapy of breast cancer. Keeping in toe with recent advances in these post-radiation therapy cutaneous changes, I would like to offer my comments in the back ground of this case.

Radiation therapy, even at low doses, can induce a wide spectrum of vascular skin proliferations from benign to frankly malignant pathologies, such as cutaneous angiosarcoma. Fineberg and Rosen noted some post-radiation vascular lesions that were atypical but not really malignant, calling the vascular proliferations to be benign "atypical vascular lesions." [2] Later in a five cases series published by Diaz-Cascajo et al., it was confirmed these lesions to be benign and proposed the term "benign lymphangiomatous papules" (BLAP) after radiation therapy. [3] Post-radiation vascular changes seem to follow a spectrum with BLAP at one end and aggressive metastatic angiosarcoma at the other extreme. In the past, various terms have been assigned to this entity, including acquired (progressive) lymphangioma, lymphangioma circumscriptum, and benign lymphangioendothelioma. [4],[5] Recently, Gengler et al. examined the clinicopathologic features of 56 vascular lesions of the skin that occurred after radiotherapy for breast carcinoma, all of which had a benign clinical course though they had few features of atypical histology also. [6]

To conclude, cutaneous vascular proliferations that develop within the field of prior radiotherapy include rare aggressive tumors, such as angiosarcomas, and also benign lymphangiomatous proliferations (BLAP/plaques). One should always bear in mind that irradiated patients are at risk for developing angiosarcoma and should be keenly followed up regularly.



 
   References Top

1.
Rao AG. Acquired lymphangiectasis following surgery and radiotherapy of breast cancer. Indian J Dermatol 2015;60:106.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.
Fineberg S, Rosen PP. Cutaneous angiosarcoma and atypical vascular lesions of the skin and breast after radiation therapy for breast carcinoma. Am J Clin Pathol. 1994;102:757-63.  Back to cited text no. 2
    
3.
Diaz-Cascajo C, Borghi S, Weyers W, Retzlaff H, Requena L, Metze D. Benign lymphangiomatous papules of the skin following radiotherapy: A report of five new cases and review of the literature. Histopathology 1999;35:319-27.  Back to cited text no. 3
    
4.
Ambrojo P, Cogolludo EF, Aguilar A, Sánchez Yus E, Sánchez de Paz F. Cutaneous lymphangiectases after therapy for carcinoma of the cervix-a case with unusual clinical and histological features. Clin Exp Dermatol 1990;15:57-9.  Back to cited text no. 4
    
5.
Giannelli V, Rockley PF. Acquired lymphangiectases following mastectomy and radiation therapy. Report of a case and review of the literature. Cutis 1996;58:276-8.  Back to cited text no. 5
    
6.
Gengler C, Coindre JM, Leroux A, Trassard M, Ranchère-Vince D, Valo I, et al. Vascular proliferations of the skin after radiation therapy for breast cancer: Clinicopathologic analysis of a series in favor of a benign process: A study from the French Sarcoma Group. Cancer 2007;109:1584-98.  Back to cited text no. 6
    




 

Top
Print this article  Email this article
 
 
  Search
 
  
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Article in PDF (148 KB)
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
* Registration required (free)  


    References

 Article Access Statistics
    Viewed2235    
    Printed12    
    Emailed0    
    PDF Downloaded41    
    Comments [Add]    

Recommend this journal