Indian Journal of Dermatology
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Table of Contents 
CORRESPONDENCE
Year : 2014  |  Volume : 59  |  Issue : 6  |  Page : 613-614
Author's reply


1 Department of Dermatology, Venereology and Leprology, Hassan Institute of Medical Sciences, Hassan, Karnataka, India
2 Department of Pathology, Hassan Institute of Medical Sciences, Hassan, Karnataka, India

Date of Web Publication30-Oct-2014

Correspondence Address:
B C Ravikumar
Department of Dermatology, Venereology and Leprology, Hassan Institute of Medical Sciences, Hassan, Karnataka
India
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Source of Support: None, Conflict of Interest: None


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How to cite this article:
Ravikumar B C, Sinhasan P. Author's reply. Indian J Dermatol 2014;59:613-4

How to cite this URL:
Ravikumar B C, Sinhasan P. Author's reply. Indian J Dermatol [serial online] 2014 [cited 2020 Aug 15];59:613-4. Available from: http://www.e-ijd.org/text.asp?2014/59/6/613/143541


Sir,

We appreciate the interest shown by Piccolo V, Russo T, Ruocco E and Baroni A [1] in our article on "Psoriasis sparing the polio affected limb: Is it merely the Koebner phenomenon?". [2] According to them, our hypothesis that friction and increased weight bearing on the polio-non-affected right lower limb may be the reasons for the preponderance of lesions on that limb.is not thoroughly convincing. While agreeing with their view, we have in fact clearly conceded in our article that we could not get any other plausible explanation to clearly explain this finding clearly. However we cannot but disagree with their other suggestion that immune alterations and resultant possible neuropeptide alterations after an injury may have a role in this case. Very important thing all of us have to note here is that the neuropeptides around which this entire discussion is revolving including that of immune alterations and immune compromised cutaneous district is not at all relevant in our case. Because even though neurogenic factors are no doubt involved in psoriasis pathogenesis, they are not considered in our case as they are reported to be relevant only in diseases with sensory impairment. Sensory impairment is not a feature of Polio. We have made this very clear in our article itself. We once again thank Picollo V, Russo T, Ruocco E and Baroni A for their interest in our article and their valuable inputs.

 
   References Top

1.Picollo V, Russo T, Ruocco E, Baroni A. Selective localization or sparing of skin disorders in neurologically injured areas; an underestimated connubium. Indian J Dermatol 2014;59:612-13.  Back to cited text no. 1
    
2.Ravikumar B, Sinhasan. Psoriasis sparing the polio-affected limb: Is it merely the Koebner phenomenon? Indian J Dermatol 2014;59:505-6.  Back to cited text no. 2
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