Indian Journal of Dermatology
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CASE REPORT
Year : 2014  |  Volume : 59  |  Issue : 2  |  Page : 176-181

Radiation port cutaneous metastases: Reports of two patients whose recurrent visceral cancers presented as skin lesions at the site of previous radiation and literature review


1 Department of Dermatology, Medical School, the University of Texas Medical School at Houston, Houston, TX, USA
2 Department of Dermatology, University of California San Diego, San Diego, CA, USA

Correspondence Address:
Philip Randolph Cohen
10991 Twinleaf Ct., San Diego, CA 92131-3643
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.127680

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Radiation therapy is associated with a variety of complications, including the development of primary skin cancers in the radiated region. However, it is rare for patients with visceral cancers who are treated with radiation therapy to subsequently develop cutaneous metastasis within the radiation port. We describe two patients with internal malignancies who developed cutaneous metastases within their radiation ports following radiotherapy. In addition, we used PubMed to perform an extensive literature review and identify additional reports of cutaneous metastasis within a radiation port. We excluded patients who developed melanoma or primary skin cancers in the radiation port. We also excluded patients with non-solid organ malignancies. Herein, we summarize the characteristics of 23 additional patients who experienced radiation port cutaneous metastases and explore possible mechanisms for the occurrence of radiation port cutaneous metastases.


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