Indian Journal of Dermatology
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Year : 2013  |  Volume : 58  |  Issue : 5  |  Page : 407

Vitamin K deficiency bleeding presenting as nodular purpura in infancy: A rare and life-threatening entity

1 Department of Dermatology, Venereology and Leprosy, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India
2 Department of Pediatrics, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India

Correspondence Address:
Pratik Gahalaut
69, Silver Estate, PO-RKU, Bareilly, Uttar Pradesh - 243 006
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.117334

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Vitamin K deficiency bleeding (VKDB) disorder is an uncommon entity, which occurs due to inadequate activity of vitamin K-dependant coagulation factors. An 8-months-old exclusively breast-fed male infant presented with multiple, purpuric and nodular non-collapsible swellings on trunk of 4 days duration. Investigations revealed raised activated partial thromboplastin time and prothrombintime. Fibrinogen level and platelet counts were normal. Late VKDB usually presents as intra-cranial or mucosal hemorrhages. [1] Though skin and mucosal bleeding may occur in 1/3 rd of infants with VKDB, 'nodular purpura' is not the common presenting feature. Earlier recognition of VKDB and immediate investigation/treatment helps prevent the potentially fatal outcome of the disease. Very little is mentioned about this entity in dermatology literature.

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