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Year : 2013  |  Volume : 58  |  Issue : 4  |  Page : 330
A particularly bothersome umbilical nodule

Department of Dermatology, University of Florence, Florence, Italy

Date of Web Publication25-Jun-2013

Correspondence Address:
Laura Giorgi Vincenzo de Giorgi
Department of Dermatology, University of Florence, Piazza Indipendenza 11, 50121 Firenze
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.114004

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How to cite this article:
Rossari S, Grazzini M, Savarese I, Longo AS, Oranges T, Gori A, Massi D, de Giorgi LV. A particularly bothersome umbilical nodule. Indian J Dermatol 2013;58:330

How to cite this URL:
Rossari S, Grazzini M, Savarese I, Longo AS, Oranges T, Gori A, Massi D, de Giorgi LV. A particularly bothersome umbilical nodule. Indian J Dermatol [serial online] 2013 [cited 2019 Aug 21];58:330. Available from:

A 28-year-old woman presented with a 3-year history of a nodule measured 2 cm within the umbilical region that was increasing in size. Her past medical history and surgical history were unremarkable. Clinical examination revealed a brownish-red, elevated, dome-shaped, bilobular nodule within the umbilical depression [Figure 1]. The patient complained of episodic discharge and bleeding from the nodule, associated with intermittent pain. This lesion has been previously diagnosed as it was impetigo and it was treated unsuccessfully with topical corticosteroids and oral antibiotics. One punch biopsy (4 mm) was performed on the nodule.
Figure 1: Brownish, elevated, dome - shaped, lobular nodule within the umbilical depression (28 - year - old woman with cutaneous endometriosis)

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   Question Top

Based on the patient's history and physical examination, which one of the following is the most likely diagnosis [Table 1]?
Table 1: Selected differential diagnosis of cutaneous endometriosis

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  • Sister Mary's Joseph nodule
  • Pyogenic granuloma
  • Cutaneous endometriosis
  • Nodular melanoma

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   References Top

1.Agarwal A, Fong YF. Cutaneous endometriosis. Singapore Med J 2008;49:704-9.  Back to cited text no. 1
2.Gunes M, Kayikcioglu F, Ozturkoglu E, Haberal A. Incisional endometriosis after cesarean section, episiotomy and other gynecologic procedures. J Obstet Gynaecol Res 2005;31:471-5.  Back to cited text no. 2
3.Sina B, Deng A. Umbilical metastasis from prostate carcinoma (Sister Mary Joseph's nodule): A case report and review of literature. J Cutan Pathol 2007;34:581-3.  Back to cited text no. 3
4.Yoshida Y, Yamamoto O. Umbilical pyogenic granuloma associated with occult omphalith. Dermatol Surg 2008;34:1613-4.  Back to cited text no. 4
5.Navarrete S, Sánchez Ismayel A, Sánchez Salas R, Sánchez R, Navarrete Llopis S. Treatment of urachal anomalies: A minimally invasive surgery technique. JSLS 2005;9:422-5.  Back to cited text no. 5
6.Seo IY, Han DY, Oh SJ, Rim JS. Laparoscopic excision of a urachal cyst containing large stones in an adult. Yonsei Med J 2008;49:869-71.  Back to cited text no. 6
7.Barth A, Wanek LA, Morton DL. Prognostic factors in 1,521 melanoma patients with distant metastases. J Am Coll Surg 1995;181:193-201.  Back to cited text no. 7
8.Erkurt MA, Aydogdu I, Kuku I, Kaya E, Basaran Y. Nodular melanoma presenting with rapid progression and widespread metastases: A case report. J Med Case Rep 2009;3:50.  Back to cited text no. 8


  [Figure 1], [Figure 2]

  [Table 1]


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