Indian Journal of Dermatology
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Year : 2013  |  Volume : 58  |  Issue : 3  |  Page : 244

Baboon syndrome induced by hydroxyzine

Department of Dermatology, Fattouma Bourguiba Hospital, Monastir, Tunisia

Correspondence Address:
Hayet Akkari
Department of Dermatology, Fattouma Bourguiba University Hospital, Monastir 5000
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.110871

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Hydroxyzine-induced drug eruptions are very rare. We report here a typical case of drug-related Baboon syndrome or symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) which was induced by hydroxyzine in a 60-year-old man. The diagnosis was confirmed by positive patch and oral accidental provocation tests with hydroxyzine. Patch tests and oral provocation tests with cetirizine and levocetirizine were negative. A review of the literature identified only 17 reported cases of hydroxyzine-induced drug eruptions. To the best of our knowledge, we report here the first case of hydroxyzine-induced SDRIFE.

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