Indian Journal of Dermatology
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E–CASE REPORT
Year : 2012  |  Volume : 57  |  Issue : 6  |  Page : 504

Extensive hypertrophic lupus erythematosus: Atypical presentation


1 Department of Dermatology, Venereology and Leprology, Gian Sagar Medical College and Hospital, Patiala, Punjab, India
2 Department of Pathology, Gian Sagar Medical College and Hospital, Patiala, Punjab, India

Correspondence Address:
Tarun Narang
Department of Deramtology, Venereology and Leprology, PGIMER, Chandigarh - 160014
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.103085

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Lupus erythematosus (LE) is a disease with a wide spectrum of cutaneous and systemic manifestations. Clinical features of patients with LE show a great variation, and for this reason it is difficult to develop a unifying concept of this disease. Our objective is to present a case of hypertrophic LE with atypical morphology and extensive involvement, who responded favorably to isotretinoin. Diagnosis of hypertrophic lupus erythematosus (HLE) was confirmed by characteristic histopathological findings. Combination therapy with isotretinoin and hydroxychloroquine resulted in flattening and repression of previously refractory skin lesions. Sometimes, HLE lesions may present a diagnostic and therapeutic dilemma. In long standing lesions, squamous cell carcinoma may arise. Therefore, HLE requires adequate therapy with clinical and histopathological follow up.


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