Indian Journal of Dermatology
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CASE REPORT
Year : 2012  |  Volume : 57  |  Issue : 1  |  Page : 58-60

Multisystem langerhans cell histiocytosis in adult


1 Department of Dermatology, Venereology and Leprosy, RNT Medical College, Udaipur, Rajasthan, India
2 Department of Dermatology, Venereology and Leprosy, Kasturba Medical College, Mangalore, Karnataka, India

Correspondence Address:
Anubhav Garg
71- A, Madhuban, Hospital Road, Udaipur-313001, Rajasthan
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.92683

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Langerhans cell histiocytosis (LCH), is a rare disorder, clinically presents with heterogeneous manifestations, and has an unpredictable outcome. Commonly seen in infancy or early childhood, the disorder is characterized by proliferation of abnormal and clonal Langerhans cell in skin, bone, lymph nodes, lungs, liver, spleen, and bone marrow. Occurrence of LCH in adults is rare. Here, we report the case of an adult with acute onset of polymorphic eruptions all over the body, which on biopsy showed features of multisystem LCH, and was confirmed by immunohistochemistry. Although multisystem LCH has a poor prognosis, our patient responded well to chemotherapy.


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