Indian Journal of Dermatology
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CME ARTICLE
Year : 2011  |  Volume : 56  |  Issue : 4  |  Page : 368-374

Cytokines in dermatology - A basic overview


Department of Dermatology, KPC Medical College, Kolkata, West Bengal, India

Correspondence Address:
Arijit Coondoo
P44A, Jogendra Gardens, Kolkata
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.84717

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Cytokines are non-immunoglobulin proteins and glycoproteins produced by a wide variety of cells, in response to any immune stimulus. Cytokines are signaling molecules that send downstream signals to various cells through a number of signal transduction pathways and act further by binding to specific membrane receptors (cytokine receptors) on the cell surface. They are emergency molecules, which are released transiently. Cytokines play an important role in cellular communication. They regulate immunity, inflammation, cell activation, cell migration, cell proliferation, apoptosis, and hematopoiesis. However, when released persistently they can produce chronic disease


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