Indian Journal of Dermatology
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CASE REPORT
Year : 2009  |  Volume : 54  |  Issue : 5  |  Page : 49-50

Reticulate variant of Darrier's disease


Department of Dermatology, Venerology and Leprosy, Nilratan Sircar Medical College, Kolkata, India

Correspondence Address:
Sudip Das
P-103 Bosenagar, Madhyamgram, 24 Parganas (N), Kolkata - 700 129
India
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Source of Support: None, Conflict of Interest: None


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Darrier disease belong to acantholytic group of disorders with loss of intraepidermal coherence. Darrier disease has an onset in puberty in the form of greasy papules, skin coloured to yellow in nature often progressing to plaques. Sites of predeliction being seborrhic areas of body. Nail abnormalities are a constant feature with a V shaped nicking.Histopathology shows orthohyperkeratoses with focal dyskeratoses, corps and ronds in stratum spinosum and grains in upper epidermis. Variable patterns have been described like bullous, haemorrhagic and linear but reticulate pattern have not been described earlier. We describe a case of reticulate variant of Darrier responding excellently to acitretin therapy.


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