Indian Journal of Dermatology
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CASE REPORT
Year : 2008  |  Volume : 53  |  Issue : 4  |  Page : 201-203

Unusual presentation of generalized macular amyloidosis in a young adult


Department of Dermatology, Kasturba Medical College, Manipal, India

Correspondence Address:
Mohan H Kudur
Department of Dermatology, Kasturba Medical College, Manipal - 576 104
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.44802

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Macular amyloidosis is a common problem seen dermatology out-patient department. Generalized macular amyloidosis presenting with a poikilodermatous appearance is rare. In our case, an 18-year-old male presented with generalized hypopigmented macules with a poikilodermatous appearance of 10-year duration. His developmental milestones were normal with negative family history of similar complaints. Histopathology of hyperpigmented lesions revealed hyperkeratosis and acanthosis of epidermis and hypopigmented lesion showing only hyperkeratosis. Both lesions were showing the deposition of amorphous, hazy material in the tips of papillary dermis with perivascular inflammatory infiltrate. Congo red staining of the amorphous material was positive for amyloid.


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