Indian Journal of Dermatology
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ORIGINAL ARTICLE
Year : 2008  |  Volume : 53  |  Issue : 3  |  Page : 115-118

Randomized comparative clinical trial of artemisia sieberi 5% lotion and clotrimazole 1% lotion for the treatment of pityriasis versicolor


1 Department of Parasitology, Kurdistan University of Medical Sciences, Iran
2 Department of Health, Kurdistan University of Medical Sciences, Iran
3 Department of Dermatology, Kurdistan University of Medical Sciences, Iran

Correspondence Address:
Farrokh Rad
Keshavarz Ave, Besat hospital, Sanandaj, Kurdistan
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.43209

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Aims: To compare the therapeutic effects of topical Artremisia sieberi 5% lotion with topical clotrimazole 1% lotion in the treatment of pityriasis versicolor. Materials and Methods: 100 patients with pityriasis versicolor and microscopic identification of Malassezia furfur were randomly assigned to treatment with either topical Artemisia sieberi 5% lotion (group 1) or topical clotrimazole 1% lotion (group 2) for 2 weeks. Group 1 and group 2 consisted of 51 and 49 patients respectively. The patients were evaluated both clinically and mycologically at baseline and every 2 weeks for a period of 4 weeks. Results: At the end of the second week, clinical cure rates were 86.3% and 65.3% for group 1 and group 2 respectively ( P <0.01), but at the same time mycological cure rate was 92.2% for group 1 and 73.5% for group 2 ( P <0.05). At the end of the fourth week, clinical cure rates were 86.3% and 59.2% for group 1 and group 2 respectively ( P <0.01), and at the same time mycologic cure rate was 96.1% for group 1 and 65.3% for group 2 ( P <0.01). Conclusions: The results of this study demonstrated that Artemisia sieberi 5% lotion was more effective than clotrimazole 1% lotion in the treatment of pityriasis versicolor.


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