Indian Journal of Dermatology
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SURGICAL PEARL
Year : 2006  |  Volume : 51  |  Issue : 2  |  Page : 142-144

Study of transplantation of melanocyte keratinocyte suspension in treatment of vitiligo


Department Dermatology, Smt. N. H. L Medical College, V. S. Hospital, Ahmedabad, Gujarat - 380006, India

Correspondence Address:
R C Rawal
2, Friends Avenue, Pakwan Cross Road, 100 Feet Bopal Road, S. G. Highway, Bodekdev, Ahmedabad - 380059
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.26941

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Background: Vitiligo is a common skin disease; however it still remains a difficult disease to treat. Not all patients respond to current forms of treatment. Surgical techniques offer a potential solution for patients with vitiligo who fail to respond to medical treatments. Aims: Aims of the study were to evaluate response of transplantation of melanocyte keratinocyte cell suspension in patients of stable vitiligo. Materials and Methods: Total 10 patients of stable localized vitiligo were included in the study and were treated with transplantation of autologous melanocyte keratinocyte suspension after motor/manual dermabrasion. Results: Out of total 10 patients, 40% [4 patients] had excellent [95 to 100%] response, 30% [3 patients] had good [65 to 94%] response, 20% [2 patients] had fair [20 to 64%] response and 10% [1 patient] had poor response [0 to 19%]. Age and sex of the patients and size and location of lesions, did not show significant influence on results of transplantation. Conclusion: Autologus melanocyte keratinocyte suspension combined with motor/manual dermabrasion is an effective affordable treatment for patients with stable vitiligo who fail to respond to medical treatments.


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