Indian Journal of Dermatology
  Publication of IADVL, WB
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Year : 2004  |  Volume : 49  |  Issue : 4  |  Page : 177-180

A Topic Diathesis In Hereditary Ichthyosis Patients Attending A Tertiary Health Care Center In Saudi Arabia


Correspondence Address:
Omar M Al-Amro Al-Akloby


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The occurrence of atopic diathesis in hereditary ichthyosis (HI) has not been documented in Saudi patients. The atopic manifestations in histopathologically confirmed HI patients attending the dermatology clinic of king Fahad Hospital of the University at Al-Khobar city, Saudi Arabia is discussed in this study. From the dermatology OPD logbook, all Saudi patients with confirmed HI seen between January 1990 to December 1995 were included in the study. The findings regarding atopic manifestations were extracted into data collection forms and analyzed. During the 5 year study period, 10,455 new cases were seen in our dermatology OPD. Of these, 61 had hereditary icthyosis, with 37 males and 24 females with a male to female ratio of 1.5:1. Thus, the frequency of HI among Saudi hospital attendees was 6 per 1000 new cases. The type of HI was ichthyosis vulgaris in 25 (41%) patients, X-linked recessive ichthyosis in 11 (18%), lamellar ichthyosis in 4(7%), bullous ichthyosiform erythroderma in 2 (3%) and nonbullous ichthyosiform erythroderma was seen in 19 (31%). Generalized pruritus was present in 49 (80%) cases, atopic dermatitis in , elevated serum IgE level was noted in 27 and bronchial asthma in 3 cases. Dandruff was reported in 24 cases, keratosis pilaris in15, recurrent skin infection in 7. Combination of hereditary ichthyosis, generalized pruritus and high serum IGE level was reported in 27 (44.3%) patient.


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