Indian Journal of Dermatology
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Year : 1998  |  Volume : 43  |  Issue : 3  |  Page : 108-110

Efficacy Of Pimozide In Delusion Of Parasitosis



Correspondence Address:
Kalyan Chakraborty


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Twenty patients of dulusion of parasitosis received oral pimozide (PMZ) 2 mg daily for 3 months. Trihexyphenydyl hydrochloride (THP) was administered in a dose of 4 mg daily in young adults and 2 mg daily in elderly patients for prevention of extrapyramidal side effects (EPS). Within 1-2 week of initiation of therapy, sixteen patients responded completely. In four patients, dosage of PMZ had to be increased to 4 mg daily and they responded 3-4 week after initiation of therapy. Treatment was continued for 3 months and all were symptom free. Following discontinuation of therapy, delusion reappeared but disappeared after reinstitution of PMZ therapy. EPS developed in two young patients resulting in discontinuation of pimozide.


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