Indian Journal of Dermatology
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Year : 1990  |  Volume : 35  |  Issue : 4  |  Page : 212-214

Prognostic value of immunoglobulin profile in human papilloma virus infection


Dept. of Dermatology, R.K.M. Sevaprathisthan, Calcutta & A F M C

Correspondence Address:
SP. Chattopadhyay
Dept. of Dermatology, R.K.M. Sevaprathisthan, Calcutta & A F M C

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Source of Support: None, Conflict of Interest: None


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ABSTRACT: Present study aimed at defining the prognostic value of immunoglobulin profile in human papilloma virus infection by assessing and correlating the levels of immunoglobulin with type, number, duration and response to therapy in 54 randomly selected cases from age group 8 to 42 year (male 35, female 19). Raised 1gG levels were seen maximally in all spectrum of warts (59.25 percent) followed by 1gM (40.74 percent) and 1gA (25.92 percent). It was also seen that 82 percent of cases with elevated 1gM and 1gA and 1gA were free from lesions with no recurrence at 6 months follow up with any from of treatment (electrodesiccation, 25 percent podophyllin, 50 percent trichloroacetic acid, 5 percent 5-fluorouracil). On the contrary, patients with elevated 1gG level showed poor response (64 percent) and partial response (16 percent) with recurrence of (38 percent) at the end of 6 months. Cure rate was 54 percent) with combined elevation of 1gG, 1gA and 1gM with recurrence rate of 24 percent


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