Indian Journal of Dermatology
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Year : 1989  |  Volume : 34  |  Issue : 4  |  Page : 52-55

Demonstration of acid fast bacilli in the circulating immune complex of leprosy cases and contacts


Department of Leprology, School of Tropical Medicine, Calcutta-700 073,

Correspondence Address:
S Chaudhary
Department of Leprology, School of Tropical Medicine, Calcutta-700 073

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ABSTRACT: Though bacilleamia in leprosy is an established fact but has not yet been possible to demonstrate acid fast bacill (AFB) in substantial number of cases. This is due to the fact that AFB remain bound in the serum as immune complex (IC). Dissociation of IC results release of antigen (AFB). Following IC dissociation it has been possible to demonstrate AFB in 100 percent of lepromatous cases, 60 percent of tuberculoid cases and 20 percent of contacts of active lepromatous cases.


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